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Non-coding RNAs as non-invasive diagnostic biomarkers for lung cancer
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Mina Tahernejad   , Sara Hamidiazar , Faranak Jamshidian * |
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Abstract: (67 Views) |
| Lung cancer stands as the second most prevalent cause of cancer-related mortality worldwide and is mainly influenced by delayed diagnosis, even with available therapeutic alternatives. The most recent studies indicate that non-coding RNAs (ncRNAs) are involved with maintaining homeostasis in cells, particularly in gene expression regulation. Hence dysregulation of these ncRNAs may develop cancer. ncRNAs in biofluids like blood, urine, saliva, serum, and plasma exosomes provide a non-invasive and less painful approach to detecting lung cancer progression. In this review novel studies for subclasses of ncRNAs such as long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and circular RNAs (circRNA) have been summarized to determine the most Potential biomarkers for prognose lung cancer. |
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| Keywords: Lung neoplasm, ncRNAs, lncRNA, miRNA, circRNA, Exosomes, Diagnosis diagnosis |
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Type of Study: Review |
Subject:
Human Genetics
Received: 2023/12/14 | Accepted: 2024/09/17 | Published: 2023/12/11
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