Obsessive-Compulsive Disorder (OCD) is one of the most common mental disorders that causes many problems in the occupational and social functioning of the patient. In this review article, we have tried to provide a comprehensive study of various areas of this disease, including pathophysiology, diagnosis, and especially OCD treatment strategies. It seems that the optimal treatment option for this disease is drug therapy, and among these, selective serotonin reuptake inhibitors (SSRIs) are of special importance. However, when the severity of the disease is low or moderate, non-pharmacological strategies such as behavioral therapy and sports intervention therapy may be desirable.